Specific Immune Response

Antigens & Antibodies

Any compound/ entity, which can elicit the production of antibodies in the individual is designated as an antigen. The antigen on presenting through the MHC, to B-Cells can elicit the production of globulin glycoproteins, which can neutralise the antigen, is known as antibody.

Antibody from Dr Alok Tripathi

Lymphocytes: Main Player of Specific Immunity

Lymphocytes are agranular leukocytes of vertebrates, responsible for coordination, modulation and execution of specific cellular and humoral immunity.

T-Cell Mediated Immunity from Dr Alok Tripathi

MHC: Major Histocompatibility Complex

Antigen presenting cell will not recognise, antigen until it is not presented through MHC, is a set of cell surface proteins essential for the acquired immune system to recognise foreign molecules in vertebrates, which in turn determines histocompatibility. The main function of MHC molecules is to bind to peptide fragments derived from pathogens and display them on the cell surface for recognition by the appropriate T-cells.

MHC: Major Histocompetability Complex from Dr Alok Tripathi
Antigen Processing & Presentation

Antigen presentation describes a vital immune process. Immune cells cannot penetrate other cells, which may be infected with viruses or bacteria, and thus rely on information conveyed by fragments of intracellular components being presented on major histocompatibility complex (MHC) molecules on the cell surface. Likewise, many pathogens are too large to be recognised directly by immune cells, and must first be digested into smaller fragments that can be presented by specialised antigen-presenting cells (APCs), such as dendritic cells and macrophages.

Antigen processing & presentation from Dr Alok Tripathi